In domains where users are exposed to large variations in visuo-spatial features among designs, they often spend excess time searching for common elements (features) in familiar locations. This paper contributes computational approaches to restructuring layouts such that features on a new, unvisited interface can be found quicker. We explore four concepts of familiarisation, inspired by the human visual system, to automatically generate a familiar design for each user. Given a history of previously visited interfaces, we restructure the spatial layout of the new (unseen) interface with the goal of making its elements more easily found. Familiariser is a browser-based implementation that automatically restructures webpage layouts based on the visual history of the user. Our evaluation with users provides first evidence favouring familiarisation.